Fig. 1: Isl1 expression pattern during GT urethral development. | Cell Death & Disease

Fig. 1: Isl1 expression pattern during GT urethral development.

From: LIM homeodomain transcription factor Isl1 affects urethral epithelium differentiation and apoptosis via Shh

Fig. 1

a Isl1 mRNA relative expression levels at different developmental stages in male GTs. Twenty-one-day mice pituitaries served as a positive control. Each sample contained at least four independent replications. Data were presented as means ± SEM. b, c Abridged general view of d–g1 slice position. Red line represents the urethra. d–g1 ISL1 localization in GTs at E11.5, E12.5, E15.5, and E18.5. Scale bars: d–g, 50, μm; d1–g1, 10 μm. GT, genital tubercle; Mes, genital mesenchyme; Ure, urethra; bl, bladder

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