Fig. 3: The comparison of pancreatic injury between ApoC3-tg mice with and without the administration of Poloxamer 407. | Cell Death & Disease

Fig. 3: The comparison of pancreatic injury between ApoC3-tg mice with and without the administration of Poloxamer 407.

From: Large triglyceride-rich lipoproteins in hypertriglyceridemia are associated with the severity of acute pancreatitis in experimental mice

Fig. 3: The comparison of pancreatic injury between ApoC3-tg mice with and without the administration of Poloxamer 407.

a Plasma triglyceride levels before acute pancreatitis induction and 12 h after the first injection of caerulein between wild-type mice with Poloxamer 407 administration, ApoC3-tg without Poloxamer 407 and ApoC3-tg with Poloxamer 407. b Representative photomicrographs of H&E-stained section of pancreas of these three groups after acute pancreatitis induction. c pathological scores of the pancreas between these three groups after acute pancreatitis induction. Scale bar = 500 or 100 μm. *p < 0.05 or **p < 0.01 or ***p < 0.001 vs wild-type mice with Poloxamer 407 administration. #p < 0.05 or ##p < 0.01 or ###p < 0.001 vs ApoC3-tg without poloxamer 407. Values are means ± SD of 3–4 animals per group. WT wild-type, TG triglyceride, Ed edema, Necr necrosis, Vac vacuolisation, Infl inflammation, P407 Poloxamer 407

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