Fig. 3: BIL elevated the expression level of SCN1A in MVN neurons. | Cell Death & Disease

Fig. 3: BIL elevated the expression level of SCN1A in MVN neurons.

From: Ca2+-dependent recruitment of voltage-gated sodium channels underlies bilirubin-induced overexcitation and neurotoxicity

Fig. 3: BIL elevated the expression level of SCN1A in MVN neurons.The alternative text for this image may have been generated using AI.

a, b Immunofluorescence labeling images of nuclei (blue), NeuN (green), and SCN1A (red) of control (a) and BIL group (b). Neurons with co-labeling of NeuN and SCN1A were chosen as AOI, and the mean fluorescence intensities of SCN1A from AOI were quantified in artificial units (AUs). c Statistical comparison showing larger MISCN1A in the BIL group, implicating elevated expression level of Nav1.1 after BIL treatment. ***p < 0.001, independent-samples t-test.

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