Fig. 5: Mechanical force regulated ECM-receptor interaction, focal adhesion, and TGF-β signaling pathways in hPDLs. | Cell Death & Disease

Fig. 5: Mechanical force regulated ECM-receptor interaction, focal adhesion, and TGF-β signaling pathways in hPDLs.

From: Intermittent compressive force promotes osteogenic differentiation in human periodontal ligament cells by regulating the transforming growth factor-β pathway

Fig. 5

Bioinformatic analysis demonstrated the common differentially expressed genes and heat maps in ECM-receptor interaction (a), focal adhesion (b), and TGF-β signaling (c) pathways. The significantly upregulated (d) and downregulated (e) genes were selected. The fold-change of the raw read counts from the RNA sequencing data were presented. Dotted lines indicate the normalized expression value of the unloaded control

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