Fig. 10: Changes in the distribution of cathepsin D (CD) and LAMP1 in podocytes after exposure to AGE-BSA. | Cell Death & Disease

Fig. 10: Changes in the distribution of cathepsin D (CD) and LAMP1 in podocytes after exposure to AGE-BSA.

From: Lysosome restoration to activate podocyte autophagy: a new therapeutic strategy for diabetic kidney disease

Fig. 10

Immunofluorescence staining of LAMP1 and cathepsin D (CD) in podocytes after exposure to 100 μg/ml AGE-BSA for 0, 3, 6, 12, or 36 h. The red immunofluorescence showed the leakage of CD from lysosomes into the cytoplasm that was accompanied by dispersed LAMP1 (green fluorescence). Scale bar, 10 μm

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