Table 1 Gene expression analysis of pBM(MDI) versus pBM(M-CSF)

From: ADP secreted by dying melanoma cells mediates chemotaxis and chemokine secretion of macrophages via the purinergic receptor P2Y12

Gene symbol

Gene name

Fold change

P2RY12

Purinergic receptor P2Y, G-protein coupled, 12

44.4

P2RY14

Purinergic receptor P2Y, G-protein coupled, 14

40.8

CCL13

Chemokine (C-C motif) ligand 13

33.9

F13A1

Coagulation factor XIII, A1 polypeptide

31.6

FCER2

Fc fragment of IgE, low affinity II, receptor for (CD23)

30.8

PDK4

Pyruvate dehydrogenase kinase, isozyme 4

28.8

GLDN

Gliomedin

22.9

ADORA3

Adenosine A3 receptor

21.3

CD200R1

CD200 receptor 1

20.1

LYVE1

Lymphatic vessel endothelial hyaluronan receptor 1

15.0

DAAM2

Disheveled associated activator of morphogenesis 2

14.5

EPS8

Epidermal growth factor receptor pathway substrate 8

12.1

SESN1

Sestrin 1

12.0

SEP3

Septin 3

11.7

MAOA

Monoamine oxidase A

11.3

CD209

CD209 molecule

11.2

FGL2

Fibrinogen-like 2

10.2

SHMT1

Serine hydroxymethyltransferase 1 (soluble)

9.5

MTSS1

Metastasis suppressor 1

9.1

SOCS1

Suppressor of cytokine signaling 1

9.1

  1. CD14+ pBM were isolated from the blood of three healthy donors and stimulated for 7 days with M-CSF or MDI. Microarray analysis was performed and the gene fold change of MDI versus M-CSF-treated pBM was calculated. Only the 20 highest up-regulated genes are shown
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