Table 1 Effects on viability of chaetocin to GC cells and GES-1

From: ROS-mediated inactivation of the PI3K/AKT pathway is involved in the antigastric cancer effects of thioredoxin reductase-1 inhibitor chaetocin

Cell line

IC50 (nM)

GES-1

>300

SNU-216

185.7 ± 13.9

HGC-27

141.80 ± 19.6

SGC-7901

133.9 ± 12.8

BGC-823

104.4 ± 4.3

AGS

51.7 ± 7.8

MKN-45

31.0 ± 5.6

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