Fig. 3: Ionizing radiation potentiates TDEC vessel formation in vivo. | Cell Death & Disease

Fig. 3: Ionizing radiation potentiates TDEC vessel formation in vivo.

From: Ionizing radiation induces endothelial transdifferentiation of glioblastoma stem-like cells through the Tie2 signaling pathway

Fig. 3: Ionizing radiation potentiates TDEC vessel formation in vivo.

a MatrigelTM plug assays using TDEC IR− or TDEC IR+ obtained from SRC3 GSC stained by hematoxylin-eosin (upper panel). Immunofluorescence of plugs using a specific anti human-CD31 antibody (lower panel). Arrows indicate functional blood vessels and headed arrows indicate hCD31+ vessels. Scale bars, 50 µm. b Quantification of functional blood vessels in MatrigelTM plugs/mm2. The number of vessels containing red blood cells per mm2 was quantified by histological analysis and was expressed as means ± SEM of 4 mice. c Quantification of hCD31+ vessels in MatrigelTM plugs/mm2. The number of hCD31 vessels per mm2 was quantified and expressed as means ± SEM of 4 mice

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