Fig. 6: Increase in the percentage of Tie2+ vessels in recurrent GBM.

a Representative IHC images for Tie2 expression in primary untreated tumors and post-radiation recurrent tumors from matched GBM patients. Arrows indicate functional blood vessels. Scale bars: 50 mm. b Percentage of Tie2 positive-vessels in primary untreated tumors and post-radiation recurrent tumors from matched GBM patients (n = 6). Each color is associated with one patient. *P < 0.05, by matched-pairs non-parametric Wilcoxon Signed Rank test