Fig. 1: PTP1B overexpression indicated the poor prognosis for pancreatic cancer patients.
From: Inhibition of PTP1B blocks pancreatic cancer progression by targeting the PKM2/AMPK/mTOC1 pathway
a, c PTP1B expression in tissues were detected by immunohistochemistry (IHC) assays (scale bar, 200 μm and 50 μm). b, d Staining index of PTP1B in tumor and nonneoplastic tumor tissue. e PTP1B protein levels in normal pancreatic ductal cell line (HPDE) and different pancreatic cell lines were examined by Western blotting. f Kaplan–Meier analysis of the correlation between PTP1B level and overall survival of pancreatic cancer patients (log-rank test p = 0.001).
