Fig. 2: ART treatment increases the KLF6 expression in WERI-Rb1 cells. | Cell Death & Disease

Fig. 2: ART treatment increases the KLF6 expression in WERI-Rb1 cells.

From: Artesunate induces mitochondria-mediated apoptosis of human retinoblastoma cells by upregulating Kruppel-like factor 6

Fig. 2: ART treatment increases the KLF6 expression in WERI-Rb1 cells.

a Microarray analysis was used to screen altered genes in WERI-Rb1 cells after ART treatment. Black dots, red dots and green dots referred to stably, upregulated, and downregulated genes, respectively. b Several cancer oncogenes and suppressors were selected to further confirmation. Through real-time PCR and western blot assay, a tumor suppressor KLF6, both mRNA (c) and protein (d, e) expression were upregulated after ART treatment. All results are presented as the mean ± SD (n = 3, *P < 0.05, vs. control)

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