Fig. 4: Altered miR-328-5p expression modulates the prolfieration, wound healing, invasion, and apoptosis of HCC cells. | Cell Death & Disease

Fig. 4: Altered miR-328-5p expression modulates the prolfieration, wound healing, invasion, and apoptosis of HCC cells.

From: CircRNA-5692 inhibits the progression of hepatocellular carcinoma by sponging miR-328-5p to enhance DAB2IP expression

Fig. 4: Altered miR-328-5p expression modulates the prolfieration, wound healing, invasion, and apoptosis of HCC cells.

Huh-7 and HepG2 cells were transfected with control or miR-328-5p mimics or transduced with control lentivirus or lentivirus for expression of miR-328-5p-specific shRNA. The relative levels of miR-328-5p expression in HCC cells were determined with qRT-PCR, and the proliferation and wound healing were examined. a MiR-328-5p expression. b The prolfieration of HCC cells. c The wound healing. d The invasion of HCC cells. e The apoptosis of HCC cells. f Western blot analysis for the relative levels of EMT-relevant protein expression in HCC cells. Data are images, charts, or expressed as the mean ± SEM of each group from three separate experiments. ##P < 0.01 vs. CON; ▵▵P < 0.01 vs. miR-OE; ▿▿P < 0.01 vs. miR-sh. OE overexpression, NC transfected with control RNA or lentivirus, Sh transduced with lentivirus for miR-328-5p-specific shRNA.

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