Fig. 7: Exogenous hypochlorous acid partially reversed ZBM-H-inhibited cell growth and ZBM-H-increased glucose-regulated protein 78 activity. | Cell Death & Disease

Fig. 7: Exogenous hypochlorous acid partially reversed ZBM-H-inhibited cell growth and ZBM-H-increased glucose-regulated protein 78 activity.

From: Inhibiting lysine 353 oxidation of GRP78 by a hypochlorous probe targeting endoplasmic reticulum promotes autophagy in cancer cells

Fig. 7

a Cell viability of A549 cells after pretreated with hypochlorous acid (0.1 μM) for 1 h, and then treated with ZBM-H (5 μM) for 12 h, n = 6. b, c Western blot analysis and quantification of phosphorylation of AMPKα (Thr172) after pretreated with hypochlorous acid (0.1, 0.5 μM) for 1 h, and then treated with ZBM-H (5 μM) for 6 h. Data are presented as the mean ± SEM, *p < 0.05, **p < 0.01, ***p < 0.001, n = 3

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