Table 1 Relationship between CAF-derived HIC-5 expression and clinicopathological characteristics in 100 ESCC tissues.
From: HIC-5 in cancer-associated fibroblasts contributes to esophageal squamous cell carcinoma progression
Variables | Number | H-score | P-value | ||
|---|---|---|---|---|---|
Low | Medium | High | |||
Esophageal cancer | 100 | 20 | 67 | 13 | |
Gender | |||||
Male | 74 | 13 | 54 | 7 | 0.802 |
Female | 26 | 7 | 13 | 6 | |
Age (year) | |||||
<60 | 30 | 7 | 20 | 3 | 0.471 |
≥60 | 70 | 13 | 47 | 10 | |
Tumor size (cm) | |||||
<5 | 42 | 6 | 30 | 6 | 0.323 |
≥5 | 43 | 9 | 30 | 4 | |
Differentiation | |||||
Well | 33 | 7 | 22 | 4 | 0.937 |
Moderately | 42 | 7 | 30 | 5 | |
Poorly | 25 | 6 | 15 | 4 | |
T stage | |||||
T1 + T2 | 15 | 6 | 8 | 1 | 0.06 |
T3 + T4 | 82 | 14 | 57 | 11 | |
Lymph node metastasis | |||||
Negative | 45 | 14 | 29 | 2 | 0.002* |
Positive | 54 | 6 | 37 | 11 | |
TNM stage | |||||
I + II | 46 | 13 | 30 | 3 | 0.029* |
III + IV | 50 | 7 | 34 | 9 | |
