Fig. 6: pSMAD2 expression in human moderately differentiated PDAC and its association with perineural invasion.
From: Schwann cells support oncogenic potential of pancreatic cancer cells through TGFβ signaling

a Hematoxylin and eosin (top images; scale bars, 200 μm) and pSMAD2 immuno histochemistry (bottom images; scale bars, 60 μm) of a representive patient with perineural invasion and a patient with no perineural invasion. Nerves are highlighted with dotted lines and tumor cells with arrows. b Distribution of tumors depending on the presence of perineural invasion and the pSMAD2 level.