Fig. 7: Mass spectrometry analysis of the secretomes of Capan-2 and sNF96.2 cells cultured alone or in combination. | Cell Death & Disease

Fig. 7: Mass spectrometry analysis of the secretomes of Capan-2 and sNF96.2 cells cultured alone or in combination.

From: Schwann cells support oncogenic potential of pancreatic cancer cells through TGFβ signaling

Fig. 7: Mass spectrometry analysis of the secretomes of Capan-2 and sNF96.2 cells cultured alone or in combination.

a Venn diagram showing the number of proteins quantified in Capan-2 CM, sNF96.2 CM and sNF96.2/Capan-2 CM, using LFQ mass spectrometry. b Principal component analysis of LFQ mass spectrometry data performed using the Proteome Discover 2.2 software. Each dot represents a CM sample, and the percentages of total variance are shown in brackets. c Hierarchical clustering of secreted proteins identified in Capan-2 CM, sNF96.2 CM and sNF96.2/Capan-2 CM. Color code is representative of the log10 normalized LFQ abundance values. d Hierarchical clustering of the indicated TGFβ superfamily members in Capan-2 CM, sNF96.2 CM and sNF96.2/Capan-2 CM. Color code is representative of the log10 normalized LFQ abundance values. CM conditioned medium, LFQ label-free quantitative.

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