Table 1 Glioblastoma patient-derived cell line models, age at diagnosis, survival, EC50 of JQ1 and TMZ.
From: BET and Aurora Kinase A inhibitors synergize against MYCN-positive human glioblastoma cells
Cell line | Age | Survival (days) | Subtype | JQ1 EC50 (nM) | EC50 TMZ (µM) |
|---|---|---|---|---|---|
U3005MG | 65 | 26 | PN | 128.4 | 418.7 |
U3009MG | 60 | 174 | CL | 122.4 | 481.5 |
U3013MGaa | 78 | 122 | PN | 537.7 | 381.7 |
U3013MGba | 78 | 122 | PN | 386.7 | 579.2 |
U3020MG | 68 | 160 | MS | 118.3 | 462.8 |
U3021MG | 50 | 387 | PN | 970.2 | 301.8 |
U3024MG | 73 | 170 | MS | 605.9 | 192.1 |
U3027MG | 44 | 766 | MS | 386 | 343.1 |
U3028MG | 72 | 496 | CL | 331.7 | 353 |
U3037MG | 60 | 333 | MS | 307.4 | 471.2 |
U3042MG | 67 | 202 | CL | 132.8 | 375.3 |
U3054MG | 60 | 611 | MS | 1124 | 589.8 |
U3056MG | 68 | 110 | CL | 94.42 | 297.2 |
U3073MG | 71 | 481 | MS | 233.7 | 343.5 |
U3082MG | 70 | 314 | PN | 786 | 193.3 |
U3084MG | 72 | 444 | CL | 7.855 | 157.6 |
U3086MG | 72 | 444 | CL | 171,7 | 663.5 |
U3110MG | 58 | 243 | MS | 433.4 | 379.9 |
U3117MG | 57 | 793 | PN | 486.5 | 456 |
