Fig. 4: PINK1 increases mitochondrial mass and ROS and inhibits HCC proliferation. | Cell Death & Disease

Fig. 4: PINK1 increases mitochondrial mass and ROS and inhibits HCC proliferation.

From: Hypoxia regulates the mitochondrial activity of hepatocellular carcinoma cells through HIF/HEY1/PINK1 pathway

Fig. 4

a Mitochondrial mass, b ROS in Huh7-NTC and shPINK1 subclones exposed to 20 and 1% O2 for 24 h. c Huh7-NTC, -shPINK1-01, shPINK1-93 cells were exposed to 20 and 1% O2 for 24 h. Cell images under transmission electron microscope (TEM). d Proliferation of Huh7-NTC and shPINK1 subclones exposed to 20 and 1% O2 for 4 days. Data are presented as mean ± s.d. (Student’s t-test, *P < 0.05, **P < 0.01, ***P < 0.001).

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