Fig. 1: HFD-induced decreases in semen quality and testosterone production in mice. | Cell Death & Disease

Fig. 1: HFD-induced decreases in semen quality and testosterone production in mice.

From: Oxidized-LDL inhibits testosterone biosynthesis by affecting mitochondrial function and the p38 MAPK/COX-2 signaling pathway in Leydig cells

Fig. 1: HFD-induced decreases in semen quality and testosterone production in mice.The alternative text for this image may have been generated using AI.

a The body weight of mice was measured every week, and the curve of body weight was plotted. b Sperm count was counted in a haemocytometer under a light microscope. c Sperm motility was analyzed by computer-assisted semen analysis. d–g Serum FSH, serum LH, serum testosterone, and serum SHBG levels were detected by ELISA. *P < 0.05, **P < 0.01, compared with SD-fed mice. h Hematoxylin and eosin (H&E) staining of histological sections of testicles in SD- and HFD-fed mice (n = 8 per group; scale bar, 200 μm).

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