Fig. 5: SNHG14/PABPC1 promotes cell proliferation and angiogenesis via inhibiting PTEN pathway. | Cell Death & Disease

Fig. 5: SNHG14/PABPC1 promotes cell proliferation and angiogenesis via inhibiting PTEN pathway.

From: LncRNA SNHG14 promotes hepatocellular carcinoma progression via H3K27 acetylation activated PABPC1 by PTEN signaling

Fig. 5

a IHC analysis of PTEN and VEGF in HCC and paired adjacent normal tissues. Scale bar, 50 μm. b The VEGF level in cell culture supernatant was determined by ELISA assay. c Protein levels of PTEN and VEGF in L02 and HCC cells were determined by western blotting. β-actin served as a loading control. d Protein levels of the key components of PTEN signaling were determined by western blotting. β-actin served as a loading control. e Clonogenic ability was determined by colony formation assay. f In vitro angiogenesis was quantified by tube formation assays. Data were representative images or were expressed as the mean ± SD of n = 3 experiments. *P < 0.05, **P < 0.01, ***P < 0.001.

Back to article page