Fig. 6: LINC01559 affected GC development by targeting PTEN and PGK1. | Cell Death & Disease

Fig. 6: LINC01559 affected GC development by targeting PTEN and PGK1.

From: Exosome-transferred LINC01559 promotes the progression of gastric cancer via PI3K/AKT signaling pathway

Fig. 6

a–d The rescue effects of PTEN and PGK1 on the proliferation, migration and stemness in LINC01559-silenced HGC-27/MSC-exo cells were demonstrated by colony formation, EdU (scar bar, 150μm), transwell (scar bar, 180μm) and sphere formation assays (scar bar, 150μm). One-way ANOVA. e, f Tumor growth curve and tumor weight were shown. For Fig. 6e, the statistical method was two-way ANOVA while for Fig. 6f was Student’s T-test. g IHC measured Ki-67 and PCNA positivity in indicated tumors. h RT-qPCR detected LINC01559, PGK1, and PTEN expression in xenografts from indicated groups. Student’s T-test. *P < 0.05, **P < 0.01.

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