Fig. 3: PTPRM inhibits cell apoptosis in vitro. | Cell Death & Disease

Fig. 3: PTPRM inhibits cell apoptosis in vitro.

From: High expression of PTPRM predicts poor prognosis and promotes tumor growth and lymph node metastasis in cervical cancer

Fig. 3: PTPRM inhibits cell apoptosis in vitro.The alternative text for this image may have been generated using AI.

a, b PTPRM mRNA and protein expression level in 7 CCa cell lines and normal cervix derived cell line H8. c–f qRT-PCR and Western blot confirmed the efficiency of PTPRM knockdown and overexpression. g, h Flow cytometry analysis for Annexin V-APC and PI staining in CCa cells transfected with siRNAs or plasmids for 72 h. i, j Bax, Bcl-2, cleaved caspase-9 and cleaved caspase-3 expression after PTPRM knockdown or overexpression *, ** or ***: significantly different from the corresponding control, P < 0.05, P < 0.01 or P < 0.001, respectively.

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