Table 2 Multivariate Cox′s proportional hazards model analysis of disease-free survival and overall survival.

From: High expression of PTPRM predicts poor prognosis and promotes tumor growth and lymph node metastasis in cervical cancer

Variables

Overall survival

Disease-free survival

 

HR (95% CI)

P-value

HR (95% CI)

P-value

Tumor size (cm)

 

0.013*

 

0.006**

 ≤4 (ref)

1

 

1

 

 >4

3.327 (1.284–8.621)

 

3.241 (1.398–7.509)

 

LVSI

 

0.005**

 

0.003**

 Negative (ref)

1

 

1

 

 Positive

3.807 (1.495–9.695)

 

3.805 (1.590–9.104)

 

LNM

 

0.025*

 

0.016*

 Negative (ref)

1

 

1

 

 Positive

2.812 (1.136–6.959)

 

2.764 (1.205–6.340)

 

PTPRM

 

0.038*

 

0.018*

 Low (ref)

1

 

1

 

 High

2.517 (1.091–21.439)

 

4.403 (1.286–15.075)

 
  1. HR hazard ratio, CI confidence interval, LNM lymph node metastasis, LVSI lymphovascular space invasion, ref reference.
  2. For the stepwise multivariate analysis, forward LR method was used to select significant variables. Variables entered for multivariate analysis were the following: tumor size, FIGO stage, LNM, LVSI, PTPRM. *P < 0.05, **P < 0.01, ***P < 0.001.
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