Fig. 3: T3 treatment promoted mitophagy via Pink1 pathway.
From: Dual effects of thyroid hormone on neurons and neurogenesis in traumatic brain injury
a Representative electron micrographs of the mouse cortex. Mitochondrion was engulfed by vacuolar structures (arrow). Mt mitochondrion. Scale bar, 1 µm. b–d T3 decreased of the mitochondrial markers of TOM40, MnSOD, and COXIV in Pink1+/+ mice but not in Pink1−/− mice (*P < 0.05, #P > 0.05). e–g T3 increased co-localization of GFP-LC3 and mitochondria (arrows) versus control in Pink1+/+ mice after TBI but not in Pink1−/− mice (Scale bar, 20 µm. *P < 0.05, #P > 0.05).
