Fig. 7: WTAP/ HMBOX1 was involved the progression of osteosarcoma via PI3K/AKT pathway.
From: WTAP promotes osteosarcoma tumorigenesis by repressing HMBOX1 expression in an m6A-dependent manner
a Western blot analysis for the expression of pPI3K, PI3K, pAKT, and AKT in osteosarcoma cells. b Cell proliferation, c colony formation, transwell invasion, and wound-healing assay of osteosarcoma cell treated with 5 μM Akt inhibitor LY294002 (Abcam, ab120243) for 12 h.
