Fig. 2: LINC00675 promotes prostate cancer (PCa) development. | Cell Death & Disease

Fig. 2: LINC00675 promotes prostate cancer (PCa) development.

From: LINC00675 activates androgen receptor axis signaling pathway to promote castration-resistant prostate cancer progression

Fig. 2: LINC00675 promotes prostate cancer (PCa) development.

a Knockdown efficiency of LINC00675 in LNCaP-SF and LNCaP-C4-2b via lentivirus transfection. n = 3. b Cell viability of LNCaP-SF and LNCaP-C4-2b with LINC00675 knockdown were determined by CCK-8 kit. c Colony-formation assay of LNCaP-SF and LNCaP-C4-2b with LINC00675 knockdown. Left: representative images of colony formation; right: quantitative analysis of colonies numbers per well. n = 3. d Cell cycle changes of LNCaP-SF and LNCaP-C4-2b with LINC00675 knockdown were determined by flow cytometry. e Migration assay of LNCaP with LINC00675 overexpression and LNCaP-SF with LINC00675 knockdown. Left: representative images of migrated cells; right: quantitative analysis of cell numbers. Scale bar: 20 μm. n = 3. Data are represented as mean ± SD. **P < 0.01; ***P < 0.001.

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