Fig. 4: TRPA1 mediates inflammation in damaged retinal tissue.
From: TRPA1 mediates damage of the retina induced by ischemia and reperfusion in mice
a, b Representative images and total number of F4/80+ cells in retina from (a) Trpa1+/+ and Trpa1−/− mice after ischemia and reperfusion (I/R) and b C57BL/6J mice after I/R and treated daily with eye drops (5 µl, 10 mM) A-967079 (A96) or its vehicle (Veh). All data are from retinas collected at day-7 after I/R. Control (CTL) indicates mice receiving all the procedures except I/R. Scale bar: 50 µm. Arrowheads, F4/80+ cells. Data are expressed as the percentage difference (Δ%) from CTL, and displayed as mean ± SEM, n = 5 mice per group. *P < 0.05 between indicated groups; two-way ANOVA and Bonferroni post hoc test.
