Fig. 1: Inhibition of UCHL1 diminishes foam cell formation. | Cell Death & Disease

Fig. 1: Inhibition of UCHL1 diminishes foam cell formation.

From: Deubiquitination of CD36 by UCHL1 promotes foam cell formation

Fig. 1

a Macrophages were exposed to DMSO, oxLDL (50 μg/ml), LDN57444 (20 μM), and LDN57444 + oxLDL for 24 h. b UCHL1 siRNA retreated for 24 h, then adding oxLDL for additional 24 h in macrophages. Oil red O was applied to stain cells. The showed images were from three independent experiments. c, d The quantitative analysis of oil red O stained cells were counted. *p < 0.05, **p < 0.01, ***p < 0.001 versus oxLDL treatment group.

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