Fig. 3: Hoxaas3 is a transcriptional target of the TGF-β1/Smad4 pathway. | Cell Death & Disease

Fig. 3: Hoxaas3 is a transcriptional target of the TGF-β1/Smad4 pathway.

From: LncRNA Hoxaas3 promotes lung fibroblast activation and fibrosis by targeting miR-450b-5p to regulate Runx1

Fig. 3

a qPCR analysis of Hoxaas3 levels in lung fibroblasts treated with TGF-β1. b, c The efficiency of the Smad4 knockdown was assessed via qPCR (b) and western blot (c). d qPCR analysis of Hoxaas3 after Smad4 knockdown with or without TGF-β1. e ChIP assays showed the level of Smad4 binding to the promoter of Hoxaas3; IgG was used as a negative control. (All data are presented as mean ± SD, n = 3, *P < 0.05).

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