Table 3 Clinicopathological associations of both DNER and β-catenin expression in breast cancer.

From: DNER promotes epithelial–mesenchymal transition and prevents chemosensitivity through the Wnt/β-catenin pathway in breast cancer

Variables

Low

N = 70

High

N = 36

P value*

Age at diagnosis, years

  

0.945

≤50

19 (27.1)

10 (27.8)

 

>50

51 (72.9)

26 (72.2)

 

Grade

  

0.038

Well

15 (21.4)

2 (5.6)

 

Moderately

19 (27.2)

7 (19.4)

 

Poorly

36 (51.4)

27 (75.0)

 

Tumour size (cm)

  

0.004

≤2

38 (54.3)

9 (25.0)

 

>2

32 (45.7)

27 (75.0)

 

Lymph node metastasis

  

0.415

Negative

27 (38.6)

11 (30.6)

 

Positive

43 (61.4)

25 (69.4)

 

Vascular invasion

  

0.113

Negative

58 (82.9)

25 (69.4)

 

Positive

12 (27.1)

11 (30.6)

 

ER

  

0.665

Negative

58 (82.9)

31 (86.1)

 

Positive

12 (27.1)

5 (13.9)

 

PR

  

0.003

Negative

40 (57.1)

31 (86.1)

 

Positive

30 (42.9)

5 (13.9)

 

HER2

  

0.057

Negative

46 (65.7)

30 (83.3)

 

Positive

24 (34.3)

6 (16.7)

 

Ki67

  

0.183

<14 %

55 (78.6)

24 (66.7)

 

≥14 %

15 (21.4)

12 (33.3)

 

Recurrence

  

< 0.01

No

62 (88.6)

20 (55.6)

 

Yes

8 (11.4)

16 (44.4)

 
  1. *P values calculated by log-rank testing; bold if statistically significant, P < 0.05.
  2. ER oestrogen receptor, PR progesterone receptor, HER2 human epithelial growth factor receptor-2.