Table 1 Clinicopathological characteristics of the 88 patients.

From: Melatonin suppresses chronic restraint stress-mediated metastasis of epithelial ovarian cancer via NE/AKT/β-catenin/SLUG axis

Histological type

FIGO

number

Age (years)

Volume (cm3)

NE IHC score

β-catenin IHC score

Ovarian cyst

 Serous

–

8

40.8 ± 15.1

–

2.03 ± 1.28###

2.53 ± 2.81###

 Mucous

–

9

Ovarian cancer

 Serous

I

4

54.4 ± 11.5

40.7 ± 37.2

3.82 ± 1.19*

3.73 ± 2.49*

 

II

18

 

III

16

54.1 ± 8.1

30.04 ± 26.92

5.00 ± 1.33

6.19 ± 2.83

 Mucous

I

5

52.1 ± 14.0

51.4 ± 38.0

3.61 ± 1.10

2.50 ± 2.31

 

II

7

 

III

2

 Mixed

I

1

47.4 ± 17.3

46.9 ± 42.7

4.58 ± 1.19

2.79 ± 2.70

 

II

1

 Endometrioid

II

4

 Clean cell

I

1

 

II

3

 Germ cell

I

4

 MMMT

II

1

 Sex cord-mesenchymal

II

3

 TCC

III

1

  1. Human ovarian tumor tissue microarrays were used to evaluate the content of NE and the expression of β-catenin in tumor tissues obtained from patients with ovarian cyst and ovarian carcinoma.
  2. FIGO International Federation of Gynecology and Obstetrics, NE norepinephrine, IHC score immunohistochemistry score, MMMT ovarian malignant mesoderm mixed tumor, TCC ovarian transitional cell carcinoma.
  3. *P < 0.05; ***P or ###P < 0.001.
  4. a * represents the Comparison of the IHC scores of NE or β-catenin between phase I/II serous ovarian cancer group and phase III serous ovarian cancer group.
  5. b # represents the Comparison of the IHC scores of NE or β-catenin between ovarian cyst group and phase I/II serous ovarian cancer group.
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