Fig. 4: BMSC-Exo inhibit NSCLC cell progression and mouse tumor growth in NSCLC. | Cell Death & Disease

Fig. 4: BMSC-Exo inhibit NSCLC cell progression and mouse tumor growth in NSCLC.

From: Bone marrow mesenchymal stem cells-derived exosomal microRNA-193a reduces cisplatin resistance of non-small cell lung cancer cells via targeting LRRC1

Fig. 4: BMSC-Exo inhibit NSCLC cell progression and mouse tumor growth in NSCLC.The alt text for this image may have been generated using AI.

a Effect of BMSC-Exo on the expression of miR-193a and LRRC1 in A549 cells. b Effect of BMSC-Exo on the expression of miR-193a and LRRC1 in A549/DDP cells. c Effect of BMSC-Exo on the expression of miR-193a and LRRC1 in H1299 cells. d Effect of BMSC-Exo on the expression of miR-193a and LRRC1 in H1299/DDP cells. e Impacts of BMSC-Exo on colony formation ability of A549 and A549/DDP cells. f Impacts of BMSC-Exo on colony formation ability of H1299 and H1299/DDP cells. g Impacts of BMSC-Exo on proliferation ability of A549 and A549/DDP cells. h Impacts of BMSC-Exo on proliferation ability of H1299 and H1299/DDP cells. i Impacts of BMSC-Exo on apoptosis of A549 and A549/DDP cells. j Impacts of BMSC-Exo on apoptosis of H1299 and H1299/DDP cells. k Impacts of BMSC-Exo on migration and invasion abilities of A549 and A549/DDP cells. l Impacts of BMSC-Exo on migration and invasion abilities of H1299 and H1299/DDP cells. m Effect of BMSC-Exo injection on A549 and A549/DDP cell tumorigenesis in nude mice. n Effect of BMSC-Exo injection on tumorigenesis of H1299 and H1299/DDP cells in nude mice. *P < 0.05 vs. the control group. Measurement data were depicted as mean ± standard deviation, comparisons between two groups were assessed by t-test. The experiment was repeated three times.

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