Fig. 1: The transcriptional landscape of PCa and paracancerous benign tissues response to ADT. | Cell Death & Disease

Fig. 1: The transcriptional landscape of PCa and paracancerous benign tissues response to ADT.

From: Immune signature driven by ADT-induced immune microenvironment remodeling in prostate cancer is correlated with recurrence-free survival and immune infiltration

Fig. 1: The transcriptional landscape of PCa and paracancerous benign tissues response to ADT.The alternative text for this image may have been generated using AI.

a Circular visualization of chromosomal positions for top DEGs 70 genes (top 35 upregulated and 35 downregulated genes) in our PCa and precancerous tissues response to ADT (innermost group: precancerous; outermost group: PCa). Black genes: DEGs in PCa tissues; blue genes: DEGs in precancerous tissues; red genes: represent co-DEGs in both tissues. b Venny diagram of DEGs in PCa and precancerous tissues. c Top 14 most frequency fusion genes in PCa and precancerous tissues pre- or post-ADT. d The box plot shows the number of fusion genes in different groups. e Representative enriched GO functions of DEGs in PCa tissues response to ADT. GO categories are grouped according to functional theme.

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