Fig. 4: miR-29b-3p inhibits breast cancer cell growth and increases sensitivity to palbociclib.
From: c-myc regulates the sensitivity of breast cancer cells to palbociclib via c-myc/miR-29b-3p/CDK6 axis
MDA-MB-231 and Hs578t cells were transfected with miR-29b-3p mimics or miR-29b-3p NC. SK-BR-3 and MCF-7 cells were transfected with miR-29b-3p inhibitor or miR-29b-3p. Then a cell viability, b cell cycle, and c colony formation were performed. d Western blot analysis of lysates from the four breast cancer cells after transfected. e IC50 of palbociclib for the four breast cancer cells after transfected. f Colony formation assays of the four breast cancer cells following the indicated transfections treated with palbociclib.
