Fig. 3: Knockdown of lncRNA Meg3 in podocytes ameliorated albuminuria and renal dysfunction in STZ-induced diabetic mice. | Cell Death & Disease

Fig. 3: Knockdown of lncRNA Meg3 in podocytes ameliorated albuminuria and renal dysfunction in STZ-induced diabetic mice.

From: Increased long noncoding RNA maternally expressed gene 3 contributes to podocyte injury induced by high glucose through regulation of mitochondrial fission

Fig. 3

a Changes of body weight measured every 2 weeks during the 12-week follow-up period. b Changes of blood glucose measured every 2 weeks during the 12-week follow-up period. c Changes of urinary urine albumin/creatinine ratio (UACR) in each group during the 12-week follow-up period. d Changes of kidney weight/body weight ratio in each group. e Changes of urine albumin excretion at the time of 12 weeks after the establishment of hyperglycemia. f Changes of blood urea nitrogen (BUN) in each group. Data were shown as mean ± SD in all statistical graphs (n = 6 mice per group). *P < 0.05 and ****P < 0.0001.

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