Fig. 8: MiR-145-5p/SPATS2 axis regulates cell apoptosis and cell cycle in HCC. | Cell Death & Disease

Fig. 8: MiR-145-5p/SPATS2 axis regulates cell apoptosis and cell cycle in HCC.

From: SPATS2, negatively regulated by miR-145-5p, promotes hepatocellular carcinoma progression through regulating cell cycle

Fig. 8

HCC cells SMMC-7721 or HepG2 were transfected with negative control (Ctrl), MiR-145-5p mimics, or MiR-145-5p mimics & SPATS2. a, b The protein expression of SPATS2, EZH2, p21, p27, survivin, c-myc, and cyclin D1 were analyzed by western blot. The experiment was repeated three times and the representative blot image was shown. c Illustrated diagram of the MiR-145-5p/SPATS2 axis working model in HCC. Results were shown as mean ± SD. *p < 0.05.

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