Table 1 Associations between DHODH expression and clinicopathological parameters of ESCC patients.
Parameters | Case number | DHODH expression | χ2 | P | |
|---|---|---|---|---|---|
Low | High | ||||
Overall | 208 | 73 | 135 | ||
Gender | |||||
Male | 162 | 54 | 108 | 0.68 | 0.41 |
Female | 46 | 19 | 27 | ||
Age (years) | |||||
≤60 | 70 | 25 | 45 | 0.03 | 0.853 |
>60 | 135 | 45 | 90 | ||
Unknown | 3 | 3 | 0 | ||
Tumor differentiation | |||||
Well | 48 | 22 | 26 | 4.26 | 0.119 |
Moderate | 120 | 41 | 79 | ||
Poor | 40 | 10 | 30 | ||
T classification | |||||
T1-2 | 29 | 14 | 15 | 1.94 | 0.164 |
T3-4 | 176 | 58 | 118 | ||
Unkown | 3 | 1 | 2 | ||
N classification | |||||
N0 | 90 | 36 | 54 | 1.32 | 0.251 |
N1-2 | 118 | 37 | 81 | ||
AJCC stage | |||||
I and II | 95 | 41 | 54 | 4.36 | 0.037* |
III and IV | 113 | 32 | 81 | ||
Status | |||||
Living | 52 | 28 | 24 | 9.63 | 0.002* |
Death | 156 | 45 | 111 | ||