Fig. 2: Enolase 1 (ENO1) promotes the stem-like characteristics of gastric cancers (GCs).
From: Enolase 1 regulates stem cell-like properties in gastric cancer cells by stimulating glycolysis
A Western blot analysis of the expression of ENO1 in PAMC-82 and SNU16 cells stably expressing pLenti-NC, pLenti-ENO1, shcon, or shENO1. B Analysis of the self-renewal abilities of PAMC-82 and SNU16 cells stably expressing pLenti-NC, pLenti-ENO1, shcon, or shENO1. Scale bar, 100 μm. C Tumorigenicity of PAMC-82 and SNU16 cells stably expressing pLenti-NC, pLenti-ENO1, shcon, or shENO1. D IHC for ENO1 in serial sections of tumor tissues from mice injected with PAMC-82 or SNU16 cells stably expressing pLenti-NC, pLenti-ENO1, shcon, or shENO1. Scale bar, 100 μm. E Expression of stem cell markers in PAMC-82 and SNU16 stable cell lines was detected by western blot. Results are from representative experiments in triplicate and shown as the mean ± standard deviation (SD). *P < 0.05, **P < 0.01, ***P < 0.001.
