Fig. 3: ZIC4 mediate the effects of EZH2 on tumor promotion in vitro.
From: Epigenetic silencing of ZIC4 contributes to cancer progression in hepatocellular carcinoma
A EZH2 and ZIC4 protein levels in HepG2 cells with or without sh-EZH2 and sh-ZIC4 treatment (n = 3). B CCK-8 assay was performed to detected cell viability of HepG2 cells with or without sh-EZH2 and sh-ZIC4 treatment (n = 5). C Colony formation assay for HepG2 cells with or without sh-EZH2 and sh-ZIC4 treatment (n = 3). D The apoptosis of HepG2 cells with or without sh-EZH2 and sh-ZIC4 treatment (n = 3). *P < 0.05, **P < 0.01 vs. control; ## P < 0.01 vs. sh-EZH2.
