Fig. 4: ZIC4 mediate the effects of EZH2 on tumor migration, invasion and EMT in vitro.
From: Epigenetic silencing of ZIC4 contributes to cancer progression in hepatocellular carcinoma
A Wound Healing assays for HepG2 cells with or without sh-EZH2 and sh-ZIC4 treatment (n = 3). B Transwell assay was performed to detected cell migration ability for HepG2 cells with or without sh-EZH2 and sh-ZIC4 treatment (n = 3). C Transwell assay was performed to detected cell invasion ability for HepG2 cells with or without sh-EZH2 and sh-ZIC4 treatment (n = 3). D EMT relative protein levels were detected in HepG2 cells with or without sh-EZH2 and sh-ZIC4 treatment (n = 3). *P < 0.05, **P < 0.01 vs. control; #P < 0.01, ##P < 0.01 vs. sh-EZH2.
