Fig. 5: BCL11B activated P73 signaling in HCC. | Cell Death & Disease

Fig. 5: BCL11B activated P73 signaling in HCC.

From: BCL11B suppresses tumor progression and stem cell traits in hepatocellular carcinoma by restoring p53 signaling activity

Fig. 5

a Cignal Finder Center 10-Pathway Reporter Array results demonstrated signaling changes in the BCL11B-knockdown MHCC97L cells and BCL11B-overexpressing Huh7 cells. b mRNA expressions of P53 signaling-related molecules was detected in indicated HCC cells. c Protein expressions of P53 signaling-related molecules was detected in indicated HCC cells. d HEK293T cells were co-transfected with indicated plasmids to investigate promotor activity of P73. e Huh7 cells were co-transfected with indicated plasmids to investigate promotor activity of P73. Means ± SD from three independent experiments are presented; *P < 0.05; **P < 0.01; ***P < 0.001.

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