Fig. 6: M-THPC-PDT treatment inhibited tumorigenesis of HCT116 subcutaneous xenografts in vivo by inducing autophagy. | Cell Death & Disease

Fig. 6: M-THPC-PDT treatment inhibited tumorigenesis of HCT116 subcutaneous xenografts in vivo by inducing autophagy.

From: Photodynamic therapy induces autophagy-mediated cell death in human colorectal cancer cells via activation of the ROS/JNK signaling pathway

Fig. 6

A Image of PDT therapy in CRC tumor-bearing nude mice. B Representative IHC images of ATG7, MAP1LC3B, and SQSTM1/p62 in tumor tissues (40× magnification). C The tumor volume of each animal was measured every other day. D Fourteen days post m-THPC-PDT treatment, xenograft tumors were photographed. All data are presented as the mean ± SD. *P < 0.05, **P < 0.01, n = 6 mice per group.

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