Fig. 2: HCCLM3exos promote the growth and metastasis of MHCC97L cells in vivo. | Cell Death & Disease

Fig. 2: HCCLM3exos promote the growth and metastasis of MHCC97L cells in vivo.

From: Exosome-derived ENO1 regulates integrin α6β4 expression and promotes hepatocellular carcinoma growth and metastasis

Fig. 2: HCCLM3exos promote the growth and metastasis of MHCC97L cells in vivo.

A A flow chart depicting the in vivo experimental design. B Evaluation of HCC growth by tumor size and number of nude mice with intrahepatic tumorigenesis in mice injected orthotopically with MHCC97L cells following education with PBS or HCCLM3exos. C Evaluation of HCC metastasis by tumor size and number of nude mice with lung metastasis in mice injected in the tail vein with MHCC97L cells following education with PBS or HCCLM3exos. For the in vivo experiments, five nude mice per group were used. A representative of three independent experiments is shown. All data are represented as mean ± SD. *P < 0.05 according to two-tailed Student’s t-test.

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