Fig. 1: YTHDC1 is induced after ischemia.
From: YTHDC1 mitigates ischemic stroke by promoting Akt phosphorylation through destabilizing PTEN mRNA
A, B Representative immunoblot (A) and quantification (B) of YTHDC1 in tissue extracts of rat brains upon 90-min MCAO followed by various time points of reperfusion. β-actin served as a loading control. C, D Representative immunoblot (C) and quantification (D) of YTHDC1 in cultured primary cortical neurons subjected to OGD/R for the indicated time points. The data are means ± S.E.M., for all panels: *P < 0.05, **P < 0.01, ***P < 0.001 by one-way ANOVA analysis; n.s., no significance. All data are representative of or combined from three independent experiments.
