Fig. 6: Gene expression profiles of key players involved in Birinapant adjuvant therapy from primary tumor tissue exhibit CMS subtype-specific patterns. | Cell Death & Disease

Fig. 6: Gene expression profiles of key players involved in Birinapant adjuvant therapy from primary tumor tissue exhibit CMS subtype-specific patterns.

From: Molecular subtype-specific responses of colon cancer cells to the SMAC mimetic Birinapant

Fig. 6: Gene expression profiles of key players involved in Birinapant adjuvant therapy from primary tumor tissue exhibit CMS subtype-specific patterns.The alternative text for this image may have been generated using AI.

Two independent CRC cohorts (Taxonomy and TCGA COAD-READ) were analyzed. Dotted line indicates a transition from linear to logarithmic space in the presence of outliers (see “Materials and methods”). Statistical analysis can be found in Supplementary File 2. Pairwise group comparisons were performed with Tukey HSD post hoc tests. P values were not adjusted for multiple comparisons as these analyses were considered exploratory. *P ≤ 0.05; **P ≤ 0.01; ***P ≤ 0.001.

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