Table 1 Cell line panel used in the study.

	MSI/MSS status	KRAS status	BRAF status	PIK3CA status	PTEN status	P53 Status	Consensus molecular subtype	CRC intrinsic subtype
RKO	MSI	WT	V600E	H1047R	Positive	WT	CMS1	CRIS-D
HT-29	MSS	WT	V600E	P449T	Positive	R273H	CMS1	CRIS-B
HCT116	MSI	G13D	WT	H1047R	Positive	WT	CMS1	CRIS-D
HCT116-p53^−/−	MSI	G13D	WT	H1047R	Positive	KO	CMS1	CRIS-E
LoVo	MSI	G13D	WT	WT	Positive	WT	CMS1	CRIS-B
GP5D	MSI	G12D	WT	H1047L	Positive	WT	CMS2	CRIS-C
LIM1215	MSI	WT	WT	WT	Positive	WT	CMS2	CRIS-C
LS1034	MSS	A146T	WT	WT	Positive	G245S	CMS2	CRIS-D
DLD-1	MSI	G13D	WT	E545K	Positive	S241F	CMS2	CRIS-A
SW620	MSS	G12V	WT	WT	Positive	R273H	CMS2	CRIS-D
C106	MSS	G13C	WT	WT	Positive	T125M	CMS2	CRIS-C
LS174T	MSI	G12D	WT	H1047R	Positive	WT	CMS3	CRIS-A
LS513	MSS	G12D	WT	WT	Positive	WT	CMS3	CRIS-E
MDST8	MSS	WT	V600K	WT	Null	WT	CMS4	CRIS-D

Quick links

Search