Fig. 2: mtDNA contributes to necroptosis-dependent intestinal injury. | Cell Death & Disease

Fig. 2: mtDNA contributes to necroptosis-dependent intestinal injury.

From: mtDNA-STING pathway promotes necroptosis-dependent enterocyte injury in intestinal ischemia reperfusion

Fig. 2: mtDNA contributes to necroptosis-dependent intestinal injury.

A Representative images of intestinal H&E, IHC (p-MLKL), and TUNEL staining in wild-type mice after the intraperitoneal injection of 5 mg/kg mtDNA or the treatment of nec-1. B Intestinal injury was assessed by Chui’s score. C Western blot was conducted to analyze necroptosis signaling. Scale bars = 50 μm. Data were shown as the mean ± SD. *P < 0.05, **P < 0.01, ***P < 0.001.

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