Fig. 6: SEMG1 and SEMG2 up-regulate glycolysis and respiration.

SeaHorse® profiling of H1299 cells with stable overexpression of SEMG1, SEMG2 or control vector. SEMGs elevate A glycolysis and B respiration; ECAR extracellular acidification rate, OCR oxygen consumption rate. C Energy map showing increased energetic status of SEMGs-overexpressing related to control cells. Three biological replicates were used for quantification, data are presented as mean ± S.D., *P < 0.05.