Fig. 3: PSTPIP2 administration suppressed CP-induced kidney dysfunction.

a PSTPIP2 mRNA levels in kidney tissue analysed by quantitative real-time PCR. b Representative efficient transfection of rAAV9–PSTPIP2–eGFP in kidney tissue detected by fluorescence microscopy. c Representative macroscopic appearance of the kidney. Kidney tissues were stained with periodic acid-Schiff and renal tubular damage was quantified. d Body weight in mice 72 h after CP injection. e Serum creatinine (Cr) assay. f Blood urea nitrogen (BUN) assay. g The protein levels of KIM-1 were detected by western blot. Similar results were obtained in 3 independent experiments with 10 mice per group.