Fig. 1: Human breast cells display differential sensitivity to MB-PDT and lipid composition. | Cell Death & Disease

Fig. 1: Human breast cells display differential sensitivity to MB-PDT and lipid composition.

From: Distinct photo-oxidation-induced cell death pathways lead to selective killing of human breast cancer cells

Fig. 1

A Cell death induction after 1, 3, or 24 h of MB-PDT treatment. B Score plot of the principal component analysis (PCA) of lipidomic data of BC. C Abundance of the glicerophospholipids: PE, oPE, pPE, PI and PG. D Abundance of lipids grouped by the degree of fatty acid chain saturation. Saturated fatty acid (SFA), monounsaturated fatty acid (MUFA), and polyunsaturated fatty acid (PUFA). E Abundance of ArA-containing lipids in BC. F Abundance of CoQ10. Dot color representation: MCF-10A in red, MCF-7 in green, MDA-MB-231 in blue. ****p < 0.0001, ***p < 0.001, **p < 0.005, *p < 0.05 vs. MCF-10A. Results are presented as mean ± SEM. Each dot represents an independent experiment. n ≥ 3 independent experiments.

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